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Both strategies are leveraged in BsADC design, with biparatopic targeting primarily aimed at enhancing receptor clustering and internalization, while Bispecific targeting across different antigens can engage distinct biological pathways or exploit differential internalization rates [14]

Rather than acting as a classic receptor agonist with a single defined binding site, BPC-157 appears to influence multiple regulatory nodes involved in endothelial signaling and cellular stress response pathways